Geoffrey J. Cutler

Machine-Directed Evolution of an Imine Reductase for Activity and Stereoselectivity

J Gilbert Eric, Elina Siirola, Charles M. Moore et al. · ACS Catalysis · 2021 · 95 citations

Engineering, Aldo-keto Reductase, Error-prone Pcr +18

5-Aryl-4-carboxamide-1,3-oxazoles: Potent and selective GSK-3 inhibitors

Gabriella Gentile, Giancarlo Merlo, Alfonso Pozzan et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 57 citations · Full text

Medicinal Chemistry, Medicine, Mechanism Of Action +6

5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-ε kinase

Paul Bamborough, J.A. Christopher, Geoffrey J. Cutler et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 51 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Ikk-ε Kinase +5

Discovery and in vitro evaluation of potent kinase inhibitors: Pyrido[1′,2′:1,5]pyrazolo[3,4-d]pyrimidines

Michael J. Alberti, Elizabeth P. Auten, Karen Lackey et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 34 citations · Full text

Drug Target, Biochemistry, Medicine +6

Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β)

J.A. Christopher, Paul Bamborough, Catherine M. Alder et al. · Journal of Medicinal Chemistry · 2009 · 30 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +14