GSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons

The selectivity of protein kinase inhibitors: a further update

Jenny Bain, Lorna Plater, Matt Elliott et al. · Biochemical Journal · 2007 · 2.5K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease

Sophie Leclerc, Matthieu Garnier, Ralph Hoessel et al. · Journal of Biological Chemistry · 2001 · 723 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death

Darren A.E. Cross, Ainsley A. Culbert, Katy Chalmers et al. · Journal of Neurochemistry · 2001 · 366 citations

Life Sciences, Biochemistry, Neuroscience +17

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

Patrice D. Smith, Stephen J. Crocker, Vernice Jackson‐Lewis et al. · Proceedings of the National Academy of Sciences · 2003 · 319 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

Lucia E. Rameh, Ching‐Shih Chen, Lewis C. Cantley · Cell · 1995 · 316 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15