Concepedia

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

Lucia E. Rameh, Ching‐Shih Chen, Lewis C. Cantley

Cell · 1995 · 316 citations · 49 references

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References

49

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.3K citations · Full text

, , +16

SH2 domains recognize specific phosphopeptide sequences

Cell · 1993 · 2.7K citations

, , +14

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Thomas Franke, Sung‐Il Yang, Tung O. Chan et al. · Cell · 1995 · 2K citations · Full text

, , +16

The insulin signaling system.

Morris F. White, C. Ronald Kahn · Journal of Biological Chemistry · 1994 · 1.7K citations · Full text

, , +10

Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

Ryoji Yao, Geoffrey M. Cooper · Science · 1995 · 1.4K citations

, , +17