Sialidase inhibitors related to zanamivir: Synthesis and biological evaluation of 4H-pyran 6-ether and ketone

Tetrapropylammonium Perruthenate, Pr₄N⁺RuO₄ ^-, TPAP: A Catalytic Oxidant for Organic Synthesis

Steven V. Ley, Joanne Norman, William P. Griffith et al. · Synthesis · 1994 · 1.2K citations

Natural Sciences, Chemistry, Catalysis +10

Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site:  Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity

Choung U. Kim, Willard Lew, Matthew A. Williams et al. · Journal of the American Chemical Society · 1997 · 1.1K citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4<i>H</i>-pyran-6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Journal of Medicinal Chemistry · 1998 · 343 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure−Activity Relationship Studies of Novel Carbocyclic Influenza Neuraminidase Inhibitors

Choung U. Kim, Willard Lew, Matthew A. Williams et al. · Journal of Medicinal Chemistry · 1998 · 290 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 2. Crystallographic and Molecular Modeling Study of Complexes of 4-Amino-4<i>H</i>-pyran-6-carboxamides and Sialidase from Influenza Virus Types A and B

Neil R. Taylor, Anne Cleasby, Onkar Singh et al. · Journal of Medicinal Chemistry · 1998 · 193 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17