The Osaka FAD Mutation E22Δ Leads to the Formation of a Previously Unknown Type of Amyloid β Fibrils and Modulates Aβ Neurotoxicity

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Robin Sherrington, Yuh‐Jin Liang, Ekaterina Rogaeva et al. · Nature · 1995 · 4K citations

Life Sciences, Genetics, Molecular Genetics +14

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

Ephrat Levy‐Lahad, Wilma Wasco, Parvoneh Poorkaj et al. · Science · 1995 · 2.6K citations

Life Sciences, Genetics, Molecular Genetics +14

3D structure of Alzheimer's amyloid-β(1–42) fibrils

Thorsten Lührs, Christiane Ritter, Marc Adrian et al. · Proceedings of the National Academy of Sciences · 2005 · 2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR

Aneta T. Petkova, Yoshitaka Ishii, John J. Balbach et al. · Proceedings of the National Academy of Sciences · 2002 · 1.8K citations

Life Sciences, Biochemistry, Biophysics +17

An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp ₇₁₇ ) Mutants

Nobuhiro Suzuki, Tobun T. Cheung, Xiao-Dan Cai et al. · Science · 1994 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +16