Topiramate slow dose titration: Improved efficacy and tolerability

A randomized, placebo-controlled study of topiramate in primary generalized tonic-clonic seizures

Victor Biton, Georgia Montouris, F. J. Ritter et al. · Neurology · 1999 · 294 citations

Medicine, Pharmacology, Pharmacotherapy +14

Topiramate Modulates GABA‐Evoked Currents in Murine Cortical Neurons by a Nonbenzodiazepine Mechanism

H. Steve White, S. D. Brown, José H. Woodhead et al. · Epilepsia · 2000 · 280 citations

Life Sciences, Neuroscience, Pharmacology +17

A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children

Roy D. Elterman, Tracy A. Glauser, Elaine Wyllie et al. · Neurology · 1999 · 234 citations

Medicine, Pediatrics, Pharmacotherapy +15

Double-blind, placebo-controlled study of topiramate in patients with refractory partial epilepsy

M. K. Sharief, C. Viteri, Elinor Ben‐Menachem et al. · Epilepsy Research · 1996 · 168 citations

Medicine, Pharmacology, Pharmacotherapy +8

A dose-comparison trial of topiramate as monotherapy in recently diagnosed partial epilepsy

Frank Gilliam, Felix Veloso, M.A.M. Bomhof et al. · Neurology · 2003 · 147 citations

Medicine, Pharmacology, Pharmacotherapy +14