dl-9a-deoky-9a-methylene PGI2 (a stable prostacyclin derivative): Preliminary pharmacological data

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

Alfred G. Gilman · Proceedings of the National Academy of Sciences · 1970 · 3.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

Ryszard J. Gryglewski, Stuart Bunting, Salvador Moncada et al. · Prostaglandins · 1976 · 1K citations

Medicine, Cardiology, Hematology +13

Chemical stability of prostacyclin (PGI2) in aqueous solutions

M.J. Cho, Meredith A. Allen · Prostaglandins · 1978 · 198 citations

Pharmacy, Biochemistry, Chemistry +9

Circulatory and anti-platelet effects of intravenous prostacyclin in healthy men

Andrzej Szczeklik, Ryszard J. Gryglewski, Rafał Niżankowski et al. · Pharmacological Research Communications · 1978 · 180 citations

Medicine, Hematology, Pharmacology +14