Glutathione induces cellular resistance against cationic dinuclear platinum anticancer drugs

Improved understanding in platinium antitumour chemistry

J. Reedijk · Chemical Communications · 1996 · 590 citations

Medicine, Chemistry, Medicinal Chemistry +12

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

Toshihisa Ishikawa, Francis Ali‐Osman · Journal of Biological Chemistry · 1993 · 538 citations · Full text

Medicine, Biochemistry, Pharmacology +16

The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines

Prakash Mistry, LR Kelland, G Abel et al. · British Journal of Cancer · 1991 · 263 citations · Full text

Medicine, Oncology, Pharmacology +14

Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance

Lloyd R. Kèlland, Swee Y. Sharp, Ciaran F. O’Neill et al. · Journal of Inorganic Biochemistry · 1999 · 207 citations

Medicine, Medicinal Chemistry, Oncology +11

DNA Modifications by a Novel Bifunctional Trinuclear Platinum Phase I Anticancer Agent

Viktor Brabec, Jana Kašpárková, Oldøich Vrána et al. · Biochemistry · 1999 · 204 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16