Decline in muscle strength and running endurance in klotho deficient C57BL/6 mice

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

Life Sciences, Genetics, Molecular Genetics +17

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Makoto Kuro‐o, Yutaka Matsumura, Hiroki Aizawa et al. · Nature · 1997 · 3.8K citations

Life Sciences, Genetics, Molecular Genetics +12

Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia

Roger A. Fielding, Bruno Vellas, William J. Evans et al. · Journal of the American Medical Directors Association · 2011 · 3.3K citations

Medicine, Geriatric Medicine, Geriatrics +16

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

Irina M. Conboy, Michael J. Conboy, Amy J. Wagers et al. · Nature · 2005 · 2.3K citations

Education, Cell Biology, Developmental Biology +14

Suppression of Aging in Mice by the Hormone Klotho

Hiroshi Kurosu, Masaya Yamamoto, Jeremy D. Clark et al. · Science · 2005 · 1.9K citations · Full text

Education, Endocrinology, Genetics +17