The ROS scavenging and renal protective effects of pH-responsive nitroxide radical-containing nanoparticles

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Pathology, Cancer Biology, Cancer Chemotherapy +17

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

Dmitri B. Kirpotin, Daryl C. Drummond, Yi Shao et al. · Cancer Research · 2006 · 1.1K citations · Full text

Nanoparticles, Does Increase Internalization, Increase Tumor Localization +17

Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property:  Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy

Younsoo Bae, Nobuhiro Nishiyama, Shigeto Fukushima et al. · Bioconjugate Chemistry · 2004 · 731 citations

Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice.

Nobuhiro Nishiyama, Souichiro Okazaki, Horacio Cabral et al. · PubMed · 2003 · 602 citations

Engineering, Solid Tumors, Biomedical Engineering +21

Long-circulating poly(ethylene glycol)–poly(d,l-lactide) block copolymer micelles with modulated surface charge

Y. Yamamoto, Yukio Nagasaki, Yukio Kato et al. · Journal of Controlled Release · 2001 · 438 citations

Block Co-polymers, Engineering, Polymer Science +6