Suppression of hLRH-1 mediated by a DNA vector-based RNA interference results in cell cycle arrest and induction of apoptosis in hepatocellular carcinoma cell BEL-7402

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

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A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

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A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

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Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors

Timothy T. Lu, Makoto Makishima, Joyce J. Repa et al. · Molecular Cell · 2000 · 1.5K citations · Full text

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A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

Guangchao Sui, Christina Soohoo, El Bachir Affar et al. · Proceedings of the National Academy of Sciences · 2002 · 1.1K citations · Full text

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