Concepedia

A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor

Yoko Yashiroda, Reika Okamoto, Kaori Hatsugai, Yasushi Takemoto, Naoki Goshima, Tamio Saito, Makiko Hamamoto, Yoshikazu Sugimoto, Hiroyuki Osada, Hiroyuki Seimiya,

Biochemical and Biophysical Research Communications · 2010 · 40 citations · 21 references

DOI

Concepts

References

21

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

, , +16

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature · 2005 · 6.7K citations

, , +16

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature · 2005 · 5.2K citations

, , +12

[56] Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

Sergio Moreno, Amar J. S. Klar, Paul Nurse · Methods in enzymology on CD-ROM/Methods in enzymology · 1991 · 3.8K citations

, , +10

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Shih-Min A. Huang, Yuji Mishina, Shanming Liu et al. · Nature · 2009 · 2.1K citations

, , +10