Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's disease

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

Life Sciences, Neurology, Neuroscience +16

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Leigh A. Holcomb, Marcia N. Gordon, Eileen McGowan et al. · Nature Medicine · 1998 · 1.4K citations

Life Sciences, Neurology, Neuroscience +17

Recognition Memory and the Human Hippocampus

Joseph R. Manns, Ramona O. Hopkins, Jonathan M. Reed et al. · Neuron · 2003 · 491 citations · Full text

Social Sciences, Neuroscience, Psychology +14

Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease

Manuela Pădurariu, Alin Ciobîcă, Lucian Hriţcu et al. · Neuroscience Letters · 2009 · 379 citations

Medicine, Neurology, Neuroscience +14

Age-related changes in learning and memory in the senescence-accelerated mouse (SAM)

Masaomi Miyamoto, Yoshihiro Kiyota, Naoki Yamazaki et al. · Physiology & Behavior · 1986 · 379 citations

Education, Neurobiology, Neuroscience +14