Publication | Closed Access
A New Method for the Synthesis of Oligodeoxyribonucleotides Bearing a 5′-Terminal Phosphate Group
20
Citations
14
References
1987
Year
Viral ReplicationBioorganic ChemistryMolecular BiologyVirus StructureBiosynthesisNucleic Acid Chemistry5′- Terminal PhosphateViral GeneticsNew Method5′-Terminal Phosphate GroupBiochemistryOligonucleotideDna ReplicationVirologyStructural Biology5′-Terminal RegionNatural SciencesNucleic Acid BiochemistryAbstract TwoMedicineSynthetic ChemistryOligodeoxyribonucleotides Bearing
Abstract Two oligoribonucleotides, pAUG and pGUAUUAAUAAUG, which are present in the 5′-terminal region of brome mosaic virus mRNA 4, have been synthesized in the phosphotriester approach involving the use of the phenylthio and anilino (or anisidino) groups as the protecting groups for the 5′- terminal phosphate.
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