Concepedia

Phosphate Protecting Groups

Phosphate Protecting Groups is a chemical strategy involving the use of specific auxiliary molecular entities that temporarily mask phosphate functionalities in nucleotide or oligonucleotide synthesis to prevent undesired side reactions, thereby enabling selective transformation of other reactive sites during the assembly of phosphorylated biomolecules.

169

Publications

5.6K

Citations

545

Authors

158

Institutions

Publications per year

2017–2026

11

Parents

Publications

169

Mononucleoside Phosphotriester Derivatives with S-Acyl-2-thioethyl Bioreversible Phosphate-Protecting Groups: Intracellular Delivery of 3'-Azido-2',3'-dideoxythymidine 5'-Monophosphate

Isabelle Lefèbvre, Christian Périgaud, Alain Pompon et al. · Journal of Medicinal Chemistry · 1995 · 232 citations

, , +8

New Photoactivated Protecting Groups. 6. <i>p</i>-Hydroxyphenacyl:  A Phototrigger for Chemical and Biochemical Probes<sup>1</sup><sup>,</sup><sup>2</sup>

Chan-Ho Park, Richard S. Givens · Journal of the American Chemical Society · 1997 · 189 citations

, , +11

Computationally Assisted Design of Polarizing Agents for Dynamic Nuclear Polarization Enhanced NMR: The AsymPol Family

Frédéric Mentink‐Vigier, Ildefonso Marín-Montesinos, Anil P. Jagtap et al. · Journal of the American Chemical Society · 2018 · 166 citations · Full text

, , +14

Rational design for cytosolic delivery of nucleoside monphosphates : “SATE” and “DTE” as enzyme-labile transient phosphate protecting groups

Christian Périgaud, Gilles Gosselin, Isabelle Lefèbvre et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 114 citations

, , +11

Zr-Based MOFs Shielded with Phospholipid Bilayers: Improved Biostability and Cell Uptake for Biological Applications

Jian Yang, Xiaojing Chen, Yongsheng Li et al. · Chemistry of Materials · 2017 · 108 citations

, , +17

1–5 of 169

Authors

545

  1. SL
    Serge L. Beaucage

    Center for Drug Evaluation and Research, United States

    14 publications · 401 citations

    12

    h-index

  2. TH
    Tsujiaki Hata

    Tokyo Institute of Technology, Japan

    10 publications · 234 citations

    10

    h-index

  3. AG
    Andrzej Grajkowski

    Center for Drug Evaluation and Research, United States

    10 publications · 274 citations

    10

    h-index

  4. MK
    Marcin K. Chmielewski

    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poland

    8 publications · 196 citations

    9

    h-index

  5. MS
    Mitsuo Sekine

    Tokyo Institute of Technology, Japan

    9 publications · 240 citations

    9

    h-index

1–5 of 545

Institutions

158

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    54 publications

    3.1K citations

  2. Tokyo Institute of Technology

    Tokyo, Japan

    10 h-index

    27 publications

    650 citations

  3. The University of Tokyo

    Tokyo, Japan

    8 h-index

    25 publications

    688 citations

  4. Université de Montpellier

    Montpellier, France

    7 h-index

    37 publications

    2.4K citations

  5. Center for Biologics Evaluation and Research

    Silver Spring, United States

    7 h-index

    29 publications

    974 citations

  6. National Cancer Institute

    Bethesda, United States

    6 h-index

    17 publications

    617 citations

  7. Laboratoire de Chimie Organique

    Paris, France

    5 h-index

    16 publications

    1.3K citations

  8. Center for Drug Evaluation and Research

    Silver Spring, United States

    5 h-index

    13 publications

    304 citations

1–8 of 158

Venues

  1. Tetrahedron Letters

    27 publications · 686 citations

    19

    h-index

  2. The Journal of Organic Chemistry

    JOC · 23 publications · 735 citations

    19

    h-index

  3. Nucleic Acids Research

    12 publications · 347 citations

    11

    h-index

  4. Journal of the American Chemical Society

    JACS · 11 publications · 636 citations

    10

    h-index

  5. Organic Letters

    OL · 10 publications · 287 citations

    10

    h-index

1–5