Concepedia

Protecting-group Strategy

A "Protecting-Group Strategy" is a synthetic methodology in organic chemistry that entails the selective masking of reactive functional groups during multistep synthesis to prevent unwanted side reactions, thereby ensuring chemoselectivity in the construction of complex molecules.

819

Publications

33.7K

Citations

2.4K

Authors

569

Institutions

Publications per year

2017–2026

60

Variants

Protecting Group StrategiesProtecting Group Strategy

Parents

Children

Publications

819

9-Fluorenylmethoxycarbonyl amino-protecting group

Louis A. Carpino, Grace Han · The Journal of Organic Chemistry · 1972 · 1K citations

, , +9

Greene's protective groups in organic synthesis

Choice Reviews Online · 2007 · 591 citations

, , +8

On the selectivity of deprotection of benzyl, mpm (4-methoxybenzyl) and dmpm (3,4-dimethoxybenzyl) protecting groups for hydroxy functions

Kiyoshi Horita, Tadao Yoshioka, Tatsuyoshi Tanaka et al. · Tetrahedron · 1986 · 509 citations

, , +5

Photosensitive protecting groups

Abraham Patchornik, Boaz Amit, R. B. Woodward · Journal of the American Chemical Society · 1970 · 472 citations

, , +5

Solid Phase Synthesis (Nobel Lecture)

R. B. Merrifield · Angewandte Chemie International Edition in English · 1985 · 356 citations

, , +14

1–5 of 819

Authors

2.4K

  1. MS
    Mitsuo Sekine

    Tokyo Institute of Technology, Japan

    11 publications · 341 citations

    11

    h-index

  2. TH
    Tsujiaki Hata

    Tokyo Institute of Technology, Japan

    10 publications · 272 citations

    10

    h-index

  3. FA
    Fernando Alberício

    Universitat de Barcelona, Spain

    10 publications · 311 citations

    10

    h-index

  4. LA
    Louis A. Carpino

    University of Massachusetts Amherst, United States

    9 publications · 1.3K citations

    9

    h-index

  5. CB
    Colin B. Reese

    King's College London, United Kingdom

    9 publications · 306 citations

    9

    h-index

1–5 of 2.4K

Institutions

569

  1. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    89 publications

    2.6K citations

  2. Universitat de Barcelona

    Barcelona, Spain

    12 h-index

    47 publications

    1.4K citations

  3. Tokyo Institute of Technology

    Tokyo, Japan

    11 h-index

    43 publications

    1.5K citations

  4. The University of Osaka

    Osaka, Japan

    10 h-index

    41 publications

    1.5K citations

  5. Laboratoire de Chimie Organique

    Paris, France

    9 h-index

    20 publications

    614 citations

  6. Tohoku University

    Sendai, Japan

    9 h-index

    32 publications

    1.4K citations

  7. Indian Institute of Chemical Technology

    Hyderabad, India

    8 h-index

    32 publications

    764 citations

  8. Chinese Academy of Sciences

    Beijing, China

    8 h-index

    29 publications

    1.4K citations

1–8 of 569

Venues

  1. Tetrahedron Letters

    208 publications · 8.1K citations

    46

    h-index

  2. The Journal of Organic Chemistry

    JOC · 101 publications · 5.5K citations

    35

    h-index

  3. Organic Letters

    OL · 61 publications · 2.1K citations

    30

    h-index

  4. Tetrahedron

    45 publications · 2.5K citations

    26

    h-index

  5. Journal of the American Chemical Society

    JACS · 26 publications · 2.1K citations

    23

    h-index

1–5