Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

Nobuya Kitaguchi, Yasuyuki Takahashi, Yasuo Tokushima, +2

Nature

Protease Inhibitory ActivityAlzheimer's DiseaseNovel PrecursorBiochemistryProtein Folding +9

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

Takashi Shirai, Hiroshi Yamaguchi, Hirataka Ito, +2

Nature

Virulence FactorPathogenesisBacteriologyPathologyEscherichia Coli +6

Solid phase synthesis of polynucleotides. VI. Farther studies on polystyrene copolymers for the solid support

Hirataka Ito, Yoshimasa Ike, Satoshi Ikuta, +1

Nucleic Acids Research

Macromolecular ChemistryBioorganic ChemistryEngineeringMolecular BiologySolid Phase Synthesis +22

Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli.

G P Vlasuk, S Inouye, Hirataka Ito, +2

Journal of Biological Chemistry

Tissue-specific expression of three types of β-protein precursor mRNA: Enhancement of protease inhibitor-harboring types in Alzheimer's disease brain

Satoshi Shiojiri, Y. Takahashi, Nobuya Kitaguchi, +5

Biochemical and Biophysical Research Communications

Neurodegenerative DiseasesMolecular NeuroscienceAlzheimer's DiseaseProteasomeDegenerative Pathology +11

Three types of amyloid protein precursor mRNA in human brain: Their differential expression in Alzheimer's disease

Seigo Tanaka, Shigenobu Nakamura, Kunihiro Ueda, +5

Biochemical and Biophysical Research Communications

Molecular NeuroscienceAlzheimer's DiseaseDifferential ExpressionDementiaMolecular Biology +8

NMR study of a synthetic DNA hairpin

Satoshi Ikuta, Rajagopal Chattopadhyaya, Hirataka Ito, +2

Biochemistry

Cloning and expression in Escherichia coli of the gene for rat tumor necrosis factor.

Takashi Shirai, Noriko Shimizu, Sadayuki HORIGUCHI, +1

Agricultural and Biological Chemistry

Enzyme specificity of proteinase inhibitor region in amyloid precursor protein of Alzheimer's disease: different properties compared with protease nexin I

Nobuya Kitaguchi, Y. Takahashi, Kiyomi Oishi, +4

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Alzheimer's DiseaseBiochemistryProtein FoldingDementiaMedicine +11

Gene Structure of Human Thrombomodulin, a Cofactor for Thrombin Catalyzed Activation of Protein C1

Takashi Shirai, Satoshi Shiojiri, Hirataka Ito, +5

The Journal of Biochemistry