Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

Nobuya Kitaguchi, Yasuyuki Takahashi, Yasuo Tokushima, +2

Nature

Protease Inhibitory ActivityAlzheimer's DiseaseNovel PrecursorBiochemistryProtein Folding +9

Functional Gene Screening System Identified TRPV4 as a Regulator of Chondrogenic Differentiation

Shuji Muramatsu, M. Wakabayashi, Takeshi Ohno, +11

Journal of Biological Chemistry

Tissue-specific expression of three types of β-protein precursor mRNA: Enhancement of protease inhibitor-harboring types in Alzheimer's disease brain

Satoshi Shiojiri, Y. Takahashi, Nobuya Kitaguchi, +5

Biochemical and Biophysical Research Communications

Neurodegenerative DiseasesMolecular NeuroscienceAlzheimer's DiseaseProteasomeDegenerative Pathology +11

Three types of amyloid protein precursor mRNA in human brain: Their differential expression in Alzheimer's disease

Seigo Tanaka, Shigenobu Nakamura, Kunihiro Ueda, +5

Biochemical and Biophysical Research Communications

Molecular NeuroscienceAlzheimer's DiseaseDifferential ExpressionDementiaMolecular Biology +8

Enzyme specificity of proteinase inhibitor region in amyloid precursor protein of Alzheimer's disease: different properties compared with protease nexin I

Nobuya Kitaguchi, Y. Takahashi, Kiyomi Oishi, +4

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Alzheimer's DiseaseBiochemistryProtein FoldingDementiaMedicine +11

Gene Structure of Human Thrombomodulin, a Cofactor for Thrombin Catalyzed Activation of Protein C1

Takashi Shirai, Satoshi Shiojiri, Hirataka Ito, +5

The Journal of Biochemistry

Mouse 2–5A synthetase cDNA: nucleotide sequence and comparison to human 2–5A synthetase

Yoshitake Ichii, Rikiro Fukunaga, Satoshi Shiojiri, +1

Nucleic Acids Research

Viral ReplicationViral Polymerase StructureGeneticsMolecular BiologyMolecular Genetics +18

Age-related changes in the proportion of amyloid precursor protein mRNAs in Alzheimer's disease and other neurological disorders

Seigo Tanaka, Li Liu, Jun Kimura, +5

Molecular Brain Research

Age-related ChangesNeurodegenerative DiseasesAlzheimer's DiseaseAgingDementia +9

Determination of amyloid β protein precursors harboring active form of proteinase inhibitor domains in cerebrospinal fluid of Alzheimer's disease patients by trypsin-antibody sandwich ELISA

Nobuya Kitaguchi, Yasuo Tokushima, Kiyomi Oishi, +6

Biochemical and Biophysical Research Communications

Neurodegenerative DiseasesProteinase InhibitorAlzheimer's DiseaseCerebrospinal FluidBiomarkers +6

Cloning and Expression in <i>Escherichia coli</i> of the Gene for Mouse Tumor Necrosis Factor

Takashi Shirai, Noriko Shimizu, Satoshi Shiojiri, +2

DNA