Concepedia

Route-Dependent Metabolism of Morphine in the Vascularly Perfused Rat Small Intestine Preparation

Margaret M. Doherty, K. Sandy Pang

Pharmaceutical Research · 2000 · 45 citations · 35 references

DOI

Concepts

References

35

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi et al. · PubMed · 1981 · 1.5K citations

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Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

Alfred H. Schinkel, Els Wagenaar, Liesbeth van Deemter et al. · Journal of Clinical Investigation · 1995 · 1.1K citations · Full text

, , +17

Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism

Mary F. Paine, Mehraneh Khalighi, Jeannine M. Fisher et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 792 citations

, , +17

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*

Kenneth S. Lown, Robert R. Mayo, Alan B. Leichtman et al. · Clinical Pharmacology & Therapeutics · 1997 · 682 citations · Full text

, , +17

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

Paul B. Watkins, Steven Wrighton, Erin G. Schuetz et al. · Journal of Clinical Investigation · 1987 · 483 citations · Full text

, , +13