Concepedia

Route-dependent Kinetics

Route-Dependent Kinetics is a toxicokinetic phenomenon in which the temporal profile of a xenobiotic's absorption, distribution, metabolism, and excretion differs quantitatively or qualitatively based on the route of administration, thereby influencing systemic exposure and toxicity.

10

Publications

299

Citations

49

Authors

19

Institutions

Publications per year

2017–2026

2

Parents

Publications

10

Cadmium-Induced Testicular Toxicity in Mice: Subacute and Subchronic Route-Dependent Effects

Viviane Gorete Silveira Mouro, Verônica Andrade siman, Janaína Silva et al. · Biological Trace Element Research · 2019 · 55 citations

, , +14

Opposite Effect of Diabetes Mellitus Induced by Streptozotocin on Oral and Intravenous Pharmacokinetics of Verapamil in Rats

Nan Hu, Shanshan Xie, Li Liu et al. · Drug Metabolism and Disposition · 2010 · 49 citations

, , +14

Route-Dependent Metabolism of Morphine in the Vascularly Perfused Rat Small Intestine Preparation

Margaret M. Doherty, K. Sandy Pang · Pharmaceutical Research · 2000 · 45 citations

, , +12

Physiologically based pharmacokinetic modeling of nanoceria systemic distribution in rats suggests dose- and route-dependent biokinetics

Ulrika Carlander, Tshepo Paulsen Moto, Anteneh Desalegn et al. · International Journal of Nanomedicine · 2018 · 44 citations · Full text

, , +16

Iron-Induced Metallothionein in Chick Liver: A Rapid, Route-Dependent Effect Independent of Zinc Status

James C. Fleet, Glen K. Andrews, Charles C. McCormick · Journal of Nutrition · 1990 · 30 citations

, , +9

1–5 of 10

Authors

49

  1. TK
    Takashi Kaneko

    Nagasaki University, Japan

    2 publications · 34 citations

    2

    h-index

  2. KS
    K. Sandy Pang

    University of Toronto, Canada

    1 publications · 45 citations

    1

    h-index

  3. GL
    Gàbriel L. Plaa

    Université de Montréal, Canada

    1 publications · 13 citations

    1

    h-index

  4. RL
    Richard L. Auten

    Duke Medical Center, United States

    1 publications · 16 citations

    1

    h-index

  5. PW
    P.Y. Wang

    University of Yamanashi, Japan

    1 publications · 13 citations

    1

    h-index

1–5 of 49

Institutions

19

  1. University of Yamanashi

    Kofu, Japan

    2 h-index

    8 publications

    128 citations

  2. University of Toronto

    Toronto, Canada

    1 h-index

    2 publications

    90 citations

  3. Chiba University

    Chiba, Japan

    1 h-index

    1 publications

    21 citations

  4. University of Kentucky

    Lexington, United States

    1 h-index

    1 publications

    44 citations

  5. Duke Medical Center

    Durham, United States

    1 h-index

    5 publications

    80 citations

  6. Karolinska Institutet

    Stockholm, Sweden

    1 h-index

    3 publications

    132 citations

  7. Universidade Federal de Viçosa

    Viçosa, Brazil

    1 h-index

    8 publications

    440 citations

  8. Monash University

    Melbourne, Australia

    1 h-index

    2 publications

    90 citations

1–8 of 19

Venues

  1. Toxicology and Applied Pharmacology

    TAAP · 2 publications · 34 citations

    2

    h-index

  2. Pharmaceutical Research

    1 publications · 45 citations

    1

    h-index

  3. Biological Trace Element Research

    1 publications · 55 citations

    1

    h-index

  4. Drug Metabolism and Disposition

    1 publications · 49 citations

    1

    h-index

  5. International Journal of Nanomedicine

    1 publications · 44 citations

    1

    h-index

1–5