Concepedia

Caspase‐8 and caspase‐7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF‐R1 receptosomes

Bärbel Edelmann, Uwe Bertsch, Vladimir Tchikov, Supandi Winoto‐Morbach, Cristiana Perrotta, Marten Jakob, Sabine Adam‐Klages, Dieter Kabelitz, Stefan Schütze

The EMBO Journal · 2010 · 103 citations · 55 references

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References

55

Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

Olivier Micheau, Jürg Tschopp · Cell · 2003 · 2.7K citations · Full text

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TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

Stefan Schütze, Karin Potthoff, Thomas Machleidt et al. · Cell · 1992 · 1.1K citations

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NF-κB Signals Induce the Expression of c-FLIP

Olivier Micheau, Susanne M.A. Lens, Olivier Gaide et al. · Molecular and Cellular Biology · 2001 · 803 citations · Full text

, , +17

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

Katja Wiegmann, Stefan Schütze, Thomas Machleidt et al. · Cell · 1994 · 725 citations

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Executioner caspase-3 and caspase-7 are functionally distinct proteases

J. Walsh, Sean P. Cullen, Clare Sheridan et al. · Proceedings of the National Academy of Sciences · 2008 · 602 citations · Full text

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