Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

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Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Giulio Genovese, Anna K. Kähler, Robert E. Handsaker et al. · New England Journal of Medicine · 2014 · 3.5K citations · Full text

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Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes

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PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors

William Lee, Sewit Teckie, Thomas Wiesner et al. · Nature Genetics · 2014 · 633 citations · Full text

Medicine, Cancer Biology, Oncology +11

Detectable clonal mosaicism from birth to old age and its relationship to cancer

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