Heterozygous inactivation of plasma membrane Ca2+-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability

Development of a Novel Polygenic Model of NIDDM in Mice Heterozygous for IR and IRS-1 Null Alleles

Jens C. Brüning, Jonathon N. Winnay, Susan Bonner‐Weir et al. · Cell · 1997 · 543 citations · Full text

Knockout Mouse, Developmental Biology, Irs-1 Null Alleles +10

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

Alessandra K. Cardozo, Fernanda Ortis, Joachim Størling et al. · Diabetes · 2005 · 513 citations · Full text

Calcineurin/NFAT signalling regulates pancreatic β-cell growth and function

Jeremy J. Heit, Åsa Apelqvist, Xueying Gu et al. · Nature · 2006 · 438 citations

Signal Transduction, Signaling Pathway, Pancreatic Cancer +6

β-Cell Death and Mass in Syngeneically Transplanted Islets Exposed to Short- and Long-Term Hyperglycemia

Montserrat Biarnés, Marta Montolío, Víctor Nacher et al. · Diabetes · 2002 · 410 citations · Full text

Biogenesis: Plasma membrane calcium ATPase: 15 years of work on the purified enzyme ¹

Ernesto Carafoli · The FASEB Journal · 1994 · 401 citations

Pump Activity, Molecular Biology, Cytoskeleton +21