Concepedia

Photoaffinity Labeling of the Benzodiazepine Binding Site of α1β3γ2 γ-Aminobutyric AcidA Receptors with Flunitrazepam Identifies a Subset of Ligands that Interact Directly with His102 of the α Subunit and Predicts Orientation of These within the Benzodiazepine Pharmacophore

Ruth M. McKernan, Sophie J. Farrar, Ian Collins, Frances Emms, Ayodeji A. Asuni, Kathleen Quirk, Howard B. Broughton

Molecular Pharmacology · 1998 · 46 citations · 31 references

References

31

Stoichiometry and Assembly of a Recombinant GABA<sub>A</sub>Receptor Subtype

Verena Tretter, Noosha Ehya, Karoline Fuchs et al. · Journal of Neuroscience · 1997 · 485 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

A single histidine in GABAA receptors is essential for benzodiazepine agonist binding.

H. Wieland, Hartmut Lüddens, P. H. Seeburg · Journal of Biological Chemistry · 1992 · 451 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Stoichiometry of a Recombinant GABA<sub>A</sub>Receptor

Yongchang Chang, Ruoping Wang, Sonal Barot et al. · Journal of Neuroscience · 1996 · 443 citations · Full text

Life Sciences, Biochemistry, Neuroscience +15

A fast new approach to pharmacophore mapping and its application to dopaminergic and benzodiazepine agonists

Yvonne C. Martin, Mark G. Bures, Elizabeth A. Danaher et al. · Journal of Computer-Aided Molecular Design · 1993 · 405 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents.

Giulia Puia, Stefano Vicini, Peter H. Seeburg et al. · Molecular Pharmacology · 1991 · 343 citations

Life Sciences, Neuroscience, Pharmacology +17