Concepedia

Photoaffinity Probes

Photoaffinity Probe is a chemical probe that enables covalent crosslinking of a biomolecular target upon photoactivation, thereby facilitating the identification and characterization of transient or low-affinity interactions in complex biological systems.

1.8K

Publications

74.4K

Citations

6K

Authors

1.1K

Institutions

Publications per year

2017–2026

165

Parents

Publications

1.8K

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.

Michal Harel, Isabelle J. Schalk, Laurence Ehret‐Sabatier et al. · Proceedings of the National Academy of Sciences · 1993 · 903 citations

, , +16

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 869 citations

, , +14

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

Thomas Pfeuffer · Journal of Biological Chemistry · 1977 · 459 citations · Full text

, , +14

Rat liver and kidney contain high densities of σ1 and σ2 receptors: characterization by ligand binding and photoaffinity labeling

Susan B. Hellewell, Ashley Bruce, Glen I. Feinstein et al. · European Journal of Pharmacology Molecular Pharmacology · 1994 · 437 citations

, , +12

Glycosylation of nuclear and cytoplasmic proteins. Purification and characterization of a uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase.

Robert S. Haltiwanger, Melissa A. Blomberg, Gerald W. Hart · Journal of Biological Chemistry · 1992 · 433 citations · Full text

, , +15

1–5 of 1.8K

Authors

6K

  1. BE
    Boyd E. Haley

    University of Kentucky, United States

    46 publications · 2K citations

    28

    h-index

  2. GD
    Glenn D. Prestwich

    University of Utah, United States

    34 publications · 1.2K citations

    22

    h-index

  3. YH
    Yasumaru Hatanaka

    University of Toyama, Japan

    34 publications · 1K citations

    18

    h-index

  4. EE
    Emanuel Escher

    Université de Sherbrooke, Canada

    22 publications · 620 citations

    16

    h-index

  5. LJ
    Laurence J. Miller

    Mayo Clinic in Arizona, United States

    17 publications · 733 citations

    16

    h-index

1–5 of 6K

Institutions

1.1K

  1. Harvard University

    Cambridge, United States

    28 h-index

    167 publications

    9.7K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    25 h-index

    214 publications

    6.5K citations

  3. Stony Brook University

    Stony Brook, United States

    23 h-index

    81 publications

    3.9K citations

  4. National Institutes of Health

    Bethesda, United States

    20 h-index

    84 publications

    6.4K citations

  5. Inserm

    Paris, France

    19 h-index

    152 publications

    3.8K citations

  6. University of Wisconsin–Madison

    Madison, United States

    19 h-index

    77 publications

    3K citations

  7. Kyoto University

    Kyoto, Japan

    17 h-index

    99 publications

    5.9K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    17 h-index

    94 publications

    5.5K citations

1–8 of 1.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 279 publications · 17K citations

    71

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 78 publications · 7.1K citations

    46

    h-index

  3. Biochemistry

    169 publications · 6.6K citations

    45

    h-index

  4. Journal of the American Chemical Society

    JACS · 63 publications · 4.1K citations

    38

    h-index

  5. Molecular Pharmacology

    53 publications · 1.9K citations

    27

    h-index

1–5