Concepedia

Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release

Mattia Volta, Stefano Cataldi, Dayne Beccano-Kelly, Lise N. Munsie, Igor Tatarnikov, Patrick Chou, Sabrina Bergeron, Emma Mitchell, Roscoe Lim, Jaskaran Khinda,

Parkinsonism & Related Disorders · 2015 · 48 citations · 18 references

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18

The mouse brain in stereotaxic coordinates

Jan Pieter Konsman · Psychoneuroendocrinology · 2003 · 4.1K citations

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Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

Daniel G. Healy, Mario Falchi, Sean S. O’Sullivan et al. · The Lancet Neurology · 2008 · 1.5K citations · Full text

Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

Yanping Li, Wencheng Liu, Tinmarla F. Oo et al. · Nature Neuroscience · 2009 · 536 citations · Full text

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Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice

Youren Tong, Hiroo Yamaguchi, Emilie Giaime et al. · Proceedings of the National Academy of Sciences · 2010 · 504 citations · Full text

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

Martin C. Herzig, Carine Kolly, Elke Persohn et al. · Human Molecular Genetics · 2011 · 361 citations · Full text

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