Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

Yanping Li, Wencheng Liu, Tinmarla F. Oo, +10

Nature Neuroscience

Knockout MouseNeurodegenerative DiseasesCardinal FeaturesMolecular NeuroscienceTransgenic Mouse Models +8

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an <i>in vivo</i> neurotoxin model of parkinsonism

Robert M. Silva, Vincent Ries, Tinmarla F. Oo, +10

Journal of Neurochemistry

Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

Hsiao-Chun Cheng, Sang Ryong Kim, Tinmarla F. Oo, +12

Journal of Neuroscience

Cell DeathAxon DegenerationCellular NeurobiologySocial SciencesAutophagy +14

Dopaminergic pathway reconstruction by Akt/Rheb‐induced axon regeneration

Sang Ryong Kim, Xiqun Chen, Tinmarla F. Oo, +6

Annals of Neurology

Regulation of Natural Cell Death in Dopaminergic Neurons of the Substantia Nigra by Striatal Glial Cell Line-Derived Neurotrophic Factor<i>In Vivo</i>

Tinmarla F. Oo, Nikolai Kholodilov, Robert E. Burke

Journal of Neuroscience

Glial BiologySynaptic TransmissionApoptosisCell DeathNatural Cell Death +21

Activation of Caspase‐3 in Developmental Models of Programmed Cell Death in Neurons of the Substantia Nigra

Beom S. Jeon, Nikolai Kholodilov, Tinmarla F. Oo, +5

Journal of Neurochemistry

Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain

Joanna M. Dragich, Takaaki Kuwajima, Megumi Hirose‐Ikeda, +15

eLife

MitophagyBrain DevelopmentCytoskeletonCellular NeurobiologySocial Sciences +20

Regulation of the Development of Mesencephalic Dopaminergic Systems by the Selective Expression of Glial Cell Line-Derived Neurotrophic Factor in Their Targets

Nikolai Kholodilov, Olga Yarygina, Tinmarla F. Oo, +4

Journal of Neuroscience

Expression of c‐fos, c‐jun, and N‐terminal kinase (JNK) in a Development Model of Induced Apoptotic Death in Neurons of the Substantia Nigra

Tinmarla F. Oo, Claire Henchcliffe, Daylon James, +1

Journal of Neurochemistry

JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration

Vincent Ries, Robert M. Silva, Tinmarla F. Oo, +7

Journal of Neurochemistry

Substantia NigraDouble Jnk2ApoptosisAutophagyCell Death +9