Concepedia
The EMBO Journal · 1996 · 416 citations · 43 references
Open access
Life SciencesImmunologyMicrobiologyApoptosisInnate ImmunityMicrobial PathogenesisDeath ReceptorsHost Immune ResponseInflammation In Infectious DiseaseMacrophage BiologyPhagocyte BiologyMacrophage ApoptosisMacrophage Responses To Bacteria
43
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations
Life Sciences, Cell Biology, Molecular Biology +13
A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations
Life Sciences, Immunology, Molecular Biology +12
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
Cell · 1993 · 2.5K citations · Full text
Life Sciences, Genetics, Molecular Biology +10
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
Muneesh Tewari, Long T. Quan, Karen O’Rourke et al. · Cell · 1995 · 2.4K citations · Full text
Life Sciences, Cell Biology, Molecular Biology +15
Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
Kun‐Liang Guan, J.E. Dixon · Analytical Biochemistry · 1991 · 1.8K citations
Life Sciences, Biochemistry, Molecular Biology +16