K Thirumalai

A bacterial invasin induces macrophage apoptosis by binding directly to ICE.

Yu Chen, Mitchell R. Smith, K Thirumalai et al. · The EMBO Journal · 1996 · 413 citations · Full text

Macrophage Biology, Inflammation, Pathogenesis +10

Caspase-1 Activation of IL-1β and IL-18 Are Essential for Shigella flexneri–Induced Inflammation

Philippe Sansonetti, Armelle Phalipon, Josette Arondel et al. · Immunity · 2000 · 396 citations · Full text

Inflammation, Cytokine, Inflammatory Disease +9

In vivo apoptosis in Shigella flexneri infections

Arturo Zychlinsky, K Thirumalai, Josette Arondel et al. · Infection and Immunity · 1996 · 172 citations · Full text

Microbial Pathogens, Immunology, Pathology +16

The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages

Hubert Hilbi, Yan Chen, K Thirumalai et al. · Infection and Immunity · 1997 · 161 citations · Full text

Immunotoxicology, Apoptosis, Immunology +18

IpaB, a Shigella flexneri invasin, colocalizes with interleukin-1 beta-converting enzyme in the cytoplasm of macrophages

K Thirumalai, K S Kim, Arturo Zychlinsky · Infection and Immunity · 1997 · 51 citations · Full text

Microbial Pathogens, Apoptosis, Immunology +20