Concepedia

Characterization of a 5-lipoxygenase-activating protein binding assay: correlation of affinity for 5-lipoxygenase-activating protein with leukotriene synthesis inhibition.

S. Charleson, Petpiboon Prasit, Serge Léger, John W. Gillard, Philip J. Vickers, Joseph A. Mancini, Peter Charleson, Jocelyne Guay, A. W. Ford‐Hutchinson, Jilly F. Evans

Molecular Pharmacology · 1992 · 43 citations · 0 references

Concepts

MedicineBiochemistryPharmacologyBiochemical PharmacologyMolecular PharmacologyPharmacodynamicsEicosanoid BiosynthesisEnzyme InhibitionLigand Binding5-Lipoxygenase Activation5-Lipoxygenase InhibitionAssayLeukotriene BiosynthesisLeukotriene Pathway InhibitionLeukotriene Synthesis InhibitorsLigand-binding Assay ValidationRadioligand Binding Assays