Concepedia

Ligand-binding Assay Validation

Ligand-Binding Assay Validation is the systematic process of confirming that a ligand-binding assay, which quantifies analytes through specific molecular interactions such as antigen-antibody binding, performs with established accuracy, precision, sensitivity, and reliability for its intended bioanalytical use.

205

Publications

12.5K

Citations

1.3K

Authors

380

Institutions

Publications per year

2017–2026

30

Parents

Publications

205

Quantitative Bioanalytical Methods Validation and Implementation: Best Practices for Chromatographic and Ligand Binding Assays

C.T. Viswanathan, Surendra K. Bansal, Brian Booth et al. · Pharmaceutical Research · 2007 · 815 citations

, , +16

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

Margarita García‐Calvo, JeanMarie Lisnock, Herbert G. Bull et al. · Proceedings of the National Academy of Sciences · 2005 · 768 citations

, , +14

Recommendations for the Bioanalytical Method Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Macromolecules

Binodh DeSilva, Wendell C. Smith, Russell Weiner et al. · Pharmaceutical Research · 2003 · 614 citations

, , +14

Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization

Zaneta Nikolovska‐Coleska, Renxiao Wang, Xueliang Fang et al. · Analytical Biochemistry · 2004 · 557 citations

, , +15

Workshop/conference report—Quantitative bioanalytical methods validation and implementation: Best practices for chromatographic and ligand binding assays

C.T. Viswanathan, Surendra K. Bansal, Brian Booth et al. · The AAPS Journal · 2007 · 483 citations · Full text

, , +13

1–5 of 205

Authors

1.3K

  1. GJ
    Gregor Jordan

    Roche Pharma AG (Germany), Germany

    4 publications · 52 citations

    4

    h-index

  2. BD
    Binodh DeSilva

    Bristol-Myers Squibb (United States), United States

    4 publications · 706 citations

    4

    h-index

  3. AN
    Alex N. Eberlé

    University Children’s Hospital Basel, Switzerland

    4 publications · 332 citations

    4

    h-index

  4. RF
    Roland F. Staack

    Roche Pharma AG (Germany), Germany

    4 publications · 52 citations

    4

    h-index

  5. AJ
    Alison Joyce

    Pfizer (United States), United States

    4 publications · 71 citations

    4

    h-index

1–5 of 1.3K

Institutions

380

  1. Pfizer (United States)

    New York, United States

    12 h-index

    50 publications

    1.5K citations

  2. Bristol-Myers Squibb (United States)

    New York, United States

    11 h-index

    66 publications

    3.8K citations

  3. Amgen (United States)

    Thousand Oaks, United States

    8 h-index

    15 publications

    2.3K citations

  4. Eli Lilly (United States)

    Indianapolis, United States

    6 h-index

    20 publications

    2K citations

  5. University Hospital of Basel

    Basel, Switzerland

    5 h-index

    5 publications

    370 citations

  6. Biogen (United States)

    Cambridge, United States

    5 h-index

    5 publications

    135 citations

  7. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    5 h-index

    33 publications

    18.9K citations

  8. United States Military Academy

    West Point, United States

    5 h-index

    17 publications

    731 citations

1–8 of 380

Venues

  1. Bioanalysis

    BIO · 25 publications · 615 citations

    14

    h-index

  2. Journal of Medicinal Chemistry

    12 publications · 633 citations

    12

    h-index

  3. Analytical Biochemistry

    11 publications · 964 citations

    11

    h-index

  4. The AAPS Journal

    AAPSJ · 10 publications · 722 citations

    10

    h-index

  5. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 7 publications · 608 citations

    7

    h-index

1–5