Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo.

Genomic sequencing.

George M. Church, W Gilbert · Proceedings of the National Academy of Sciences · 1984 · 8.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Efficient<i>in vitro</i>synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

Douglas A. Melton, Paul A. Krieg, Michael R. Rebagliati et al. · Nucleic Acids Research · 1984 · 6.4K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +11

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

Wes Lee, Pamela J. Mitchell, Robert Tjian · Cell · 1987 · 2K citations

Medicine, Molecular Biology, Molecular Genetics +13

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

Marc Montminy, Kevin A. Sevarino, John A. Wagner et al. · Proceedings of the National Academy of Sciences · 1986 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +16

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

William S. Dynan, Robert Tjian · Nature · 1985 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +14