Concepedia

Amniotic Fluid Derived Stem Cells with a Renal Progenitor Phenotype Inhibit Interstitial Fibrosis in Renal Ischemia and Reperfusion Injury in Rats

Marina Gabriela Monteiro Carvalho Mori da Cunha, Silvia Zia, Fanny Oliveira Arcolino, Marianne Carlon, Diego Vilibaldo Beckmann, Ney Luís Pippi, Dominguita Lühers Graça, Elena Levtchenko, Jan Deprest, Jaan Toelen

PLoS ONE · 2015 · 43 citations · 64 references

DOIFull text

Open access

Abstract

hAFSCs contain a renal progenitor cell subpopulation that has a nephroprotective effect when delivered intra-arterially in rats with renal I/R injury, and reduces interstitial fibrosis on long term follow-up.

References

64

Isolation of amniotic stem cell lines with potential for therapy

Paolo De Coppi, Georg Bartsch, Mohummad Minhaj Siddiqui et al. · Nature Biotechnology · 2007 · 1.9K citations

, , +11

Origin and function of myofibroblasts in kidney fibrosis

Valerie S. LeBleu, Gangadhar Taduri, Joyce T. O’Connell et al. · Nature Medicine · 2013 · 1.2K citations · Full text

, , +7

Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms

Florian Tögel, Zhuma Hu, Kathleen Weiss et al. · American Journal of Physiology-Renal Physiology · 2005 · 1.2K citations

, , +17

DELAYED GRAFT FUNCTION: RISK FACTORS AND IMPLICATIONS FOR RENAL ALLOGRAFT SURVIVAL1

Akinlolu Ojo, Robert A. Wolfe, Philip J. Held et al. · Transplantation · 1997 · 989 citations

, , +12

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

Sik Lee, Sarah C. Huen, Hitoshi Nishio et al. · Journal of the American Society of Nephrology · 2011 · 881 citations · Full text