CM-Dextran-Polyalcohol-Camptothecin Conjugate

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

Structure and properties of pharmacologically active polymers

Helmut Ringsdorf · Journal of Polymer Science Polymer Symposia · 1975 · 1.1K citations

Natural Sciences, Chemistry, Pharmacology +11

Preclinical evaluation of polymer-bound doxorubicin

Ruth Duncan, Leonard W. Seymour, K.B. O'Hare et al. · Journal of Controlled Release · 1992 · 188 citations

Natural Sciences, Molecular Pharmaceutics, Pharmacokinetics +12

Controlled degradation of polysaccharides by periodate oxidation, reduction, and hydrolysis

Irwin Goldstein, George W. Hay, B.A. Lewis et al. · 1965 · 184 citations

Life Sciences, Biochemistry, Food Science +12

Synthesis of Carboxymethylpullulan-Peptide-Doxorubicin Conjugates and Their Properties.

Hideo Nogusa, T. Yano, Satoshi Okuno et al. · Chemical and Pharmaceutical Bulletin · 1995 · 40 citations · Full text

Medicine, Pharmaceutics, Pharmacology +13