Concepedia

Prognostic value of PD-1 and TIM-3 on CD3+ T cells from diffuse large B-cell lymphoma

Li Zhang, Hui Du, Ji-zhu Liu, Guozhen Liu, Jingxia Wang, Guangyao Li, Lexin Wang

Biomedicine & Pharmacotherapy · 2015 · 39 citations · 17 references

DOI

Concepts

References

17

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Kaori Sakuishi, Lionel Apétoh, Jenna M. Sullivan et al. · The Journal of Experimental Medicine · 2010 · 2.1K citations · Full text

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Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients

Julien Fourcade, Zhaojun Sun, Mourad Benallaoua et al. · The Journal of Experimental Medicine · 2010 · 1.3K citations · Full text

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Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors

Shin Foong Ngiow, Bianca von Scheidt, Hisaya Akiba et al. · Cancer Research · 2011 · 567 citations

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TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells

Yoshikane Kikushige, Takahiro Shima, Shin‐ichiro Takayanagi et al. · Cell stem cell · 2010 · 482 citations · Full text

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Targeting PD-1/PD-L1 interactions for cancer immunotherapy

Laurence Zitvogel, Guido Kroemer · OncoImmunology · 2012 · 374 citations · Full text

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