Shin‐ichiro Takayanagi

TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells

Yoshikane Kikushige, Takahiro Shima, Shin‐ichiro Takayanagi et al. · Cell stem cell · 2010 · 475 citations · Full text

Hematological Malignancy, Cell Therapy, Medicine +10

TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

Satoshi Yamazaki, Atsushi Iwama, Shin‐ichiro Takayanagi et al. · Blood · 2008 · 308 citations · Full text

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

Jinghui Zhang, Kelly McCastlain, Hiroki Yoshihara et al. · Nature Genetics · 2016 · 302 citations · Full text

Hematological Malignancy, Mixed-phenotype Acute Leukemia, Hematology +4

A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

Yoshikane Kikushige, Toshihiro Miyamoto, Junichiro Yuda et al. · Cell stem cell · 2015 · 273 citations · Full text

Hematological Malignancy, Cell Therapy, Mixed-phenotype Acute Leukemia +6

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

Satoshi Yamazaki, Atsushi Iwama, Shin‐ichiro Takayanagi et al. · The EMBO Journal · 2006 · 259 citations · Full text

Inflammation, Cytokine, Signal Transduction +11