Takahiro Shima

TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells

Yoshikane Kikushige, Takahiro Shima, Shin‐ichiro Takayanagi et al. · Cell stem cell · 2010 · 482 citations · Full text

Medicine, Cell Biology, Oncology +10

Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

Yoshikane Kikushige, Fumihiko Ishikawa, Toshihiro Miyamoto et al. · Cancer Cell · 2011 · 307 citations · Full text

Medicine, Cell Biology, Hematology +16

A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

Yoshikane Kikushige, Toshihiro Miyamoto, Junichiro Yuda et al. · Cell stem cell · 2015 · 283 citations · Full text

Medicine, Cell Biology, Oncology +16

FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD–specific STAT5 activation

Goichi Yoshimoto, Toshihiro Miyamoto, Siamak Jabbarzadeh‐Tabrizi et al. · Blood · 2009 · 264 citations · Full text

Medicine, Cell Biology, Molecular Biology +17

Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment

Takuji Yamauchi, Katsuto Takenaka, Shingo Urata et al. · Blood · 2013 · 139 citations · Full text

Life Sciences, Genetics, Molecular Genetics +3