DNA-PKcs interference sensitizes colorectal cancer cells to a mTOR kinase inhibitor WAY-600

Cancer statistics, 2014

Rebecca L. Siegel, Jiemin Ma, Zhaohui Zou et al. · CA A Cancer Journal for Clinicians · 2014 · 11.6K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Identification of a PKB/Akt Hydrophobic Motif Ser-473 Kinase as DNA-dependent Protein Kinase

Jianhua Feng, Jongsun Park, Peter Cron et al. · Journal of Biological Chemistry · 2004 · 490 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

Doug W. Chan, Benjamin Ping-Chi Chen, Sheela Prithivirajsingh et al. · Genes & Development · 2002 · 463 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Preclinical Evaluation of a Potent Novel DNA-Dependent Protein Kinase Inhibitor NU7441

Yan Zhao, Huw D. Thomas, Michael A. Batey et al. · Cancer Research · 2006 · 447 citations · Full text

Medicine, Oncology, Pharmacology +16

Biochemical, Cellular, and <i>In vivo</i> Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Ker Yu, Lourdes Toral‐Barza, Celine Shi et al. · Cancer Research · 2009 · 330 citations

Medicine, Oncology, Pharmacology +13