The Amplification Loop of the Complement Pathways

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Denise Harold, Richard Abraham, Paul Hollingworth et al. · Nature Genetics · 2009 · 3.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Jean‐Charles Lambert, Simon Heath, Gaël Even et al. · Nature Genetics · 2009 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

The Properdin System and Immunity: I. Demonstration and Isolation of a New Serum Protein, Properdin, and Its Role in Immune Phenomena

Louis Pillemer, Livia Blum, Irwin H. Lepow et al. · Science · 1954 · 941 citations

Life Sciences, Biochemistry, Immunology +10

Complement C3 Variant and the Risk of Age-Related Macular Degeneration

John R.W. Yates, Tiina Sepp, Baljinder K. Matharu et al. · New England Journal of Medicine · 2007 · 828 citations · Full text

Medicine, Genetics, Ophthalmology +17

Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum

Robert A. Nelson, Joerg A. Jensen, Irma Gigli et al. · Immunochemistry · 1966 · 647 citations

Life Sciences, Biochemistry, Immunology +3