Avian Metallothioneins: Structure, Regulation and Evolution

The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein

Yoko Uchida, Koji Takio, Koiti Titani et al. · Neuron · 1991 · 707 citations

Life Sciences, Neurobiology, Neuroscience +10

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium.

B A Masters, E J Kelly, Carol J. Quaife et al. · Proceedings of the National Academy of Sciences · 1994 · 628 citations

Veterinary Medicine, Genetics, Molecular Genetics +17

MT-III, a brain-specific member of the metallothionein gene family.

R D Palmiter, S D Findley, Theodore E. Whitmore et al. · Proceedings of the National Academy of Sciences · 1992 · 564 citations

Life Sciences, Genetics, Molecular Genetics +13

Induction of a New Metallothionein Isoform (MT-IV) Occurs during Differentiation of Stratified Squamous Epithelia

Carol J. Quaife, S D Findley, Glenda J. Froelick et al. · Biochemistry · 1994 · 560 citations

Pharmacy, Biochemistry, Bioisosterism +5

The transcription factor MTF‐1 is essential for basal and heavy metal‐induced metallothionein gene expression.

Rainer Heuchel, Freddy Radtke, Oleg Georgiev et al. · The EMBO Journal · 1994 · 500 citations · Full text

Life Sciences, Genetics, Molecular Biology +8