Rainer Heuchel

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn et al. · Nature · 1997 · 1.8K citations

Molecular Physiology, Signal Transduction, Signaling Pathway +5

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

Rainer Heuchel, Freddy Radtke, Oleg Georgiev et al. · The EMBO Journal · 1994 · 495 citations · Full text

Reductive Stress, Transcriptional Regulation, Biochemistry +8

Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy

Enza Lonardo, Patrick Hermann, M Mueller et al. · Cell stem cell · 2011 · 412 citations · Full text

Lineage Plasticity, Pancreatic Cancer, Combined Drug Therapy +9

Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

Freddy Radtke, Rainer Heuchel, Oleg Georgiev et al. · The EMBO Journal · 1993 · 391 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing

Paola Longati, Xiaohui Jia, Johannes Eimer et al. · BMC Cancer · 2013 · 378 citations · Full text