Journal of Biological Chemistry · 1979 · 189 citations · 13 references
MedicineBiochemistryPharmacologyCell SignalingHemostasisSignal TransductionCell-surface ReceptorsMembrane ReceptorsPlatelet ActivationPlatelet AggregationPlatelet FunctionPlatelet PhysiologyAdenylate Cyclase RegulationAdenylate Cyclase SignalingLigand-binding Assay ValidationPlatelet Receptor BiologyPlatelet Receptor SignalingPlatelet Receptor-ligand InteractionsPlatelet Surface ReceptorsProstaglandin Physiology
(PG) regulate platelet aggregation by their action on membrane-associated adenylate cyclase. In order to define more directly platelet-prostaglandin interactions, a binding assay has been developed for platelet prostaglandin receptors using TH]-
13
A highly sensitive adenylate cyclase assay
Yoram Salomon, Constantine Londos, Martin Rodbell · Analytical Biochemistry · 1974 · 4.2K citations
Modulation of human platelet adenylate cyclase by prostacyclin (PGX)
Robert R. Gorman, S Bunting, O.V. Miller · Prostaglandins · 1977 · 655 citations
Medicine, Biochemistry, Pharmacology +10