Stromal expression of VEGF‐A and VEGFR‐2 in prostate tissue is associated with biochemical and clinical recurrence after radical prostatectomy

Abstract

This large study highlights the prognostic importance of VEGF-A and VEGFR-2 stromal expression. Analyses of these biomarkers may help distinguish which patients will benefit from radical treatment. Together with previous studies showing efficiency of targeting VEGFR-2 in prostate cancer, this study highlights its potential as a target for therapy, and may aid in future selection of prostate cancer patients for novel anti-angiogenic treatment.