Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

Phenotypic Analysis of Antigen-Specific T Lymphocytes

John D. Altman, Paul Moss, Philip Goulder et al. · Science · 1996 · 3.6K citations

Life Sciences, Cell Biology, Immunology +17

Three-dimensional segregation of supramolecular activation clusters in T cells

Colin R. F. Monks, Benjamin A. Freiberg, Hannah Kupfer et al. · Nature · 1998 · 2.3K citations

Life Sciences, Cell Biology, Molecular Biology +16

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

Daniel L. Kaufman, Michael Clare‐Salzler, Jide Tian et al. · Nature · 1993 · 1.1K citations · Full text

Life Sciences, Endocrinology, Immunology +14

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

Roland Tisch, Xiaodong Yang, Steven M. Singer et al. · Nature · 1993 · 950 citations

Medicine, Endocrinology, Immunology +12

T-cell-receptor affinity and thymocyte positive selection

S. Munir Alam, Paul Travers, Jay L. Wung et al. · Nature · 1996 · 603 citations

Life Sciences, Cell Biology, Immunology +13