Concepedia

The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

Mathias Müller, James Briscoe, Carl Laxton, Dmitry Guschin, Andrew Ziemiecki, Olli Silvennoinen, Ailsa G. Harpur, Giovanna Barbieri, Bruce A. Witthuhn, Chris Schindler,

Nature · 1993 · 771 citations · 47 references

DOI

Concepts

References

47

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

Bruce A. Witthuhn, Frederick W. Quelle, Olli Silvennoinen et al. · Cell · 1993 · 1.2K citations

, , +6

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

Lawrence S. Argetsinger, George S. Campbell, Xianjie Yang et al. · Cell · 1993 · 994 citations · Full text

, , +9

Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor

Chris Schindler, Ke Shuai, Vincent R. Prezioso et al. · Science · 1992 · 912 citations

, , +17

A protein tyrosine kinase in the interferon αβ signaling pathway

Laura Evelia Torres Velázquez, Marc Fellous, George R. Stark et al. · Cell · 1992 · 890 citations

, , +14

Activation of Transcription by IFN-γ: Tyrosine Phosphorylation of a 91-kD DNA Binding Protein

Ke Shuai, Chris Schindler, Vincent R. Prezioso et al. · Science · 1992 · 788 citations

, , +15