LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Peter J. Munson, David Rodbard

Analytical Biochemistry

EngineeringBiochemistryMedicineRational Drug DesignLigand-binding Systems +7

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

Jacques J. Peschon, Philip Morrissey, Kenneth H. Grabstein, +9

The Journal of Experimental Medicine

High Affinity ReceptorLymphocyte DevelopmentT-regulatory CellImmunologyImmune System +17

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

Ursula von Freeden-Jeffry, Paulo Vieira, Linda Lucian, +3

The Journal of Experimental Medicine

Lymphocyte DevelopmentT-regulatory CellImmunologyImmune RegulationImmature T +17

Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans

Masayuki Noguchi

Cell

Primary ImmunodeficiencyImmunogeneticsAllergyHuman RetrovirusImmunodeficiencies +5

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 Receptor

Masayuki Noguchi, Yoshiaki Nakamura, Sarah M. Russell, +4

Science

ImmunologyImmune RegulationImmunologic MechanismImmune SystemFunctional Component +15

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15.

Judith G. Giri, Minoo Ahdieh, June Eisenman, +7

The EMBO Journal

InflammationCytokineGamma ChainsNovel Cytokine Il-15Immune Regulation +8

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

Paolo Macchi, Anna Villa, Silvia Giliani, +9

Nature

Primary ImmunodeficiencyImmunogeneticsImmune DeficiencyJak-3 GeneImmunology +8

Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development

Sarah M. Russell, Nahid Tayebi, Hiroshi Nakajima, +9

Science

The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

Jian-Xin Lin, Thi-Sau Migone, Monica Tseng, +8

Immunity

InflammationCommon Stat ProteinsCytokineSignal TransductionAutoimmune Disease +9

Sharing of the Interleukin-2 (IL-2) Receptor γ Chain Between Receptors for IL-2 and IL-4

Motonari Kondo, Toshikazu Takeshita, Naoto Ishii, +4

Science