Concepedia

Discovering novel ligands for macromolecules using X-ray crystallographic screening

V. Nienaber, Paul L. Richardson, Vered Klighofer, Jennifer J. Bouska, Vincent L. Giranda, Jonathan Greer

Nature Biotechnology · 2000 · 320 citations · 16 references

DOI

Concepts

References

16

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

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[20] Processing of X-ray diffraction data collected in oscillation mode

Zbyszek Otwinowski, W. Minor · Methods in enzymology on CD-ROM/Methods in enzymology · 1997 · 33.6K citations

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A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

P. J. Goodford · Journal of Medicinal Chemistry · 1985 · 2.6K citations

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Discovering High-Affinity Ligands for Proteins: SAR by NMR

Suzanne B. Shuker, Philip J. Hajduk, Robert Meadows et al. · Science · 1996 · 2K citations

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Physiological consequences of loss of plasminogen activator gene function in mice

Peter Carmeliet, Luc Schoonjans, L Kieckens et al. · Nature · 1994 · 1.1K citations

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