Jennifer J. Bouska

ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

Cherrie K. Donawho, Yan Luo, Yanping Luo et al. · Clinical Cancer Research · 2007 · 762 citations · Full text

5-lipoxygenase inhibitory activity of zileuton.

G W Carter, Patrick Young, Daniel H. Albert et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 417 citations

Discovering novel ligands for macromolecules using X-ray crystallographic screening

V. Nienaber, Paul L. Richardson, Vered Klighofer et al. · Nature Biotechnology · 2000 · 320 citations

X-ray Crystallography, Engineering, Protein X-ray Crystallography +5

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(<i>R</i>)-2-methylpyrrolidin-2-yl]-1<i>H</i>-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Thomas D. Penning, Gui‐Dong Zhu, Viraj B. Gandhi et al. · Journal of Medicinal Chemistry · 2008 · 264 citations · Full text

Potent and selective inhibitors of Akt kinases slow the progress of tumors <i>in vivo</i>

Yan Luo, Alexander R. Shoemaker, Xuesong Liu et al. · Molecular Cancer Therapeutics · 2005 · 244 citations · Full text

Akt Kinases, Signal Transduction Pathways, Medicine +14