Concepedia

Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates

Christian Hinderer, Peter Bell, Jean-Pierre Louboutin, Yanqing Zhu, Hongwei Yu, Gloria H. Y. Lin, Ruth Choa, Brittney L. Gurda, Jessica Bagel, Patricia O’Donnell,

Molecular Therapy · 2015 · 84 citations · 40 references

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40

‘Actively Acquired Tolerance’ of Foreign Cells

R. E. Billingham, L Brent, P. B. Medawar · Nature · 1953 · 3.1K citations

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Worldwide Epidemiology of Neutralizing Antibodies to Adeno‐Associated Viruses

Roberto Calcedo, Luk H. Vandenberghe, Guangping Gao et al. · The Journal of Infectious Diseases · 2009 · 792 citations · Full text

, , +14

Mannose 6-Phosphate Receptors and Lysosomal Enzyme Targeting

Nancy Dahms, Peter Lobel, Stuart Kornfeld · Journal of Biological Chemistry · 1989 · 478 citations · Full text

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Recognition and receptor-mediated uptake of a lysosomal enzyme, α-l-iduronidase, by cultured human fibroblasts

Gloria N. Sando, Elizabeth F. Neufeld · Cell · 1977 · 355 citations

, , +11

Long-term Efficacy and Safety of Laronidase in the Treatment of Mucopolysaccharidosis I

L. Clarke, J. E. Wraith, Michael Beck et al. · PEDIATRICS · 2008 · 346 citations

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