L. Clarke

Enzyme replacement therapy for mucopolysaccharidosis I: a randomized, double-blinded, placebo-controlled, multinational study of recombinant human α-L-iduronidase (laronidase)

J. E. Wraith, L. Clarke, Michael Beck et al. · The Journal of Pediatrics · 2004 · 546 citations

Life Sciences, Biochemistry, Enzymology +7

Mucopolysaccharidosis I: Management and Treatment Guidelines

Joseph Muenzer, J. E. Wraith, L. Clarke · PEDIATRICS · 2008 · 460 citations

Medicine, Hematology, Pediatrics +10

Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm

Håkan Telenius, Berry Kremer, Y. Paul Goldberg et al. · Nature Genetics · 1994 · 451 citations

Life Sciences, Genetics, Molecular Genetics +13

A unique point mutation in the fibroblast growth factor receptor 3 gene (FGFR3) defines a new craniosynostosis syndrome.

Maximilian Muenke, Karen W. Gripp, Donna M. McDonald‐McGinn et al. · PubMed · 1997 · 394 citations

Dentistry, Genetics, Molecular Genetics +16

Long-term Efficacy and Safety of Laronidase in the Treatment of Mucopolysaccharidosis I

L. Clarke, J. E. Wraith, Michael Beck et al. · PEDIATRICS · 2008 · 346 citations

Pharmacy, Pharmacotherapy, Biopharmaceutics +12